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[婴幼儿血管瘤的皮质类固醇治疗]

[Corticosteroid for hemangioma in infants and young children].

作者信息

Lai G Q

机构信息

Tumor Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou.

出版信息

Zhonghua Zhong Liu Za Zhi. 1991 Mar;13(2):149-51.

PMID:1879295
Abstract

500 infants and young children suffering from hemangioma treated by corticosteroid (Prednisone) are reported. This disorder is most commonly seen in the head and neck (64.2%). Clinically there are 3 types of hemangioma: intradermal (34.1%), subdermal (11.3%), and mixed (51.5%). Our patients were treated with steroid (Prednisone 20-40 mg/QOD at 8 am). All patients were responsive. In 411 evaluated patients, 151 (36.7%) gave CR, 83 (20.1%) gave CR with residual telangiectasis, 172 (41.5%) gave PR, and in 5 patients, the lesion remained or slightly faded. During and within 3 years of treatment, none developed undesirable side effects, though the treatment was protracted to 2 years.

摘要

报告了500例接受皮质类固醇(泼尼松)治疗的婴幼儿血管瘤病例。这种疾病最常见于头颈部(64.2%)。临床上血管瘤有3种类型:皮内型(34.1%)、皮下型(11.3%)和混合型(51.5%)。我们的患者接受类固醇治疗(泼尼松20 - 40毫克/隔日,上午8点服用)。所有患者均有反应。在411例接受评估的患者中,151例(36.7%)完全缓解,83例(20.1%)完全缓解但有残留毛细血管扩张,172例(41.5%)部分缓解,5例患者病变无变化或略有消退。在治疗期间及治疗后3年内,尽管治疗持续了2年,但无一例出现不良副作用。

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