Waner M, Suen J Y, Dinehart S
Department of Otolaryngology, University of Arkansas for Medical Sciences, Little Rock.
Laryngoscope. 1992 Oct;102(10):1123-32. doi: 10.1288/00005537-199210000-00007.
Hemangiomas are a group of pediatric tumors that present at or soon after birth. Rapid proliferation is seen in the neonatal period, and may continue for the first year of life. Involution follows, and may last as long as 12 years. Since hemangiomas invariably involute, the vast majority have been left untreated. At least 10% to 20% of cases, however, will need active intervention, traditionally in the form of oral Prednisone. The frequent occurrence of life-threatening complications, permanent deformities, and irreversible psychosocial damage in spite of adequate steroid therapy necessitated a fresh look at the management of these lesions. Using recently developed laser technology alone or in combination with surgical excision, the authors have developed guidelines for safe intervention in all stages of the hemangioma cycle. Safe, active intervention in accordance with these guidelines offers an alternative to the more conservative approach previously advocated.
血管瘤是一组在出生时或出生后不久出现的儿科肿瘤。在新生儿期可见快速增殖,并可能持续到生命的第一年。随后进入消退期,可能持续长达12年。由于血管瘤总是会自行消退,绝大多数情况下都未进行治疗。然而,至少10%至20%的病例需要积极干预,传统上采用口服泼尼松的形式。尽管进行了充分的类固醇治疗,但仍频繁出现危及生命的并发症、永久性畸形和不可逆转的心理社会损害,这使得人们有必要重新审视这些病变的治疗方法。作者使用最近开发的激光技术单独或与手术切除相结合,制定了在血管瘤病程各阶段进行安全干预的指南。按照这些指南进行安全、积极的干预为先前倡导的更为保守的方法提供了一种替代方案。