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利福平、乙胺丁醇和吡嗪酰胺所致血小板减少症。

Rifampicin, ethambutol and pyrazinamide-induced thrombocytopenia.

作者信息

Kant S, Natu N K, Mahajan V

机构信息

Department of Pulmonary Medicine, Chhatrapati Shahuji Maharaj Medical University, Lucknow, Uttar Pradesh, India.

出版信息

Int J Clin Pharmacol Ther. 2008 Aug;46(8):440-2. doi: 10.5414/cpp46440.

Abstract

Drug-induced thrombocytopenia is an uncommon but serious side effect of many drugs including antituberculosis drugs. It is difficult to diagnose but easy to prevent just by stopping the exposure to the same drug again. In some cases, it can prove fatal if not taken care of urgently. Here, we report a case of thrombocytopenia due to rifampicin, ethambutol and pyrazinamide all in an adult male, which we believe is the first to be reported.

摘要

药物性血小板减少症是包括抗结核药物在内的许多药物罕见但严重的副作用。其诊断困难,但只要不再接触同一种药物就很容易预防。在某些情况下,如果不紧急处理,可能会导致致命后果。在此,我们报告一例成年男性因利福平、乙胺丁醇和吡嗪酰胺导致血小板减少症的病例,我们认为这是首例报告。

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