Nakamura Y, Takahashi M, Kitaguti M, Imaoka H, Kono N, Tarui S
Department of Neurology, Kinki University School of Medicine, Osaka, Japan.
Electromyogr Clin Neurophysiol. 1991 May-Jul;31(4):243-9.
Brainstem auditory evoked potentials (BAEPs) and median nerve somatosensory evoked potentials (MN-SEPs) were measured in 53 diabetic patients. Magnetic resonance imaging (MRI) was performed 12 patients with abnormal BAEPs and/or MN-SEPs in order to confirm the existence of lesions in the central nervous system. Twenty-six percent of the diabetic patients had abnormal BAEPs and three had a prolongation of the central conduction time in the MN-SEPs. MRI findings of ten of the 12 patients with abnormal BAEPs or MN-SEPs showed multiple small lesions in the pons, thalamus, and centrum semiovale etc. Two of them showed small lesion in the pontine basis which could induce prolonged interpeak latencies of BAEPs. Our MRI study might suggest that abnormal brainstem evoked potentials in diabetic patients were induced by diabetic macroangiopathy or microangiopathy.
对53例糖尿病患者进行了脑干听觉诱发电位（BAEPs）和正中神经体感诱发电位（MN-SEPs）检测。对12例BAEPs和/或MN-SEPs异常的患者进行了磁共振成像（MRI）检查，以确认中枢神经系统病变的存在。26%的糖尿病患者BAEPs异常，3例MN-SEPs的中枢传导时间延长。12例BAEPs或MN-SEPs异常的患者中，10例的MRI表现为脑桥、丘脑和半卵圆中心等部位有多个小病灶。其中2例在脑桥基底部有小病灶，可导致BAEPs峰间潜伏期延长。我们的MRI研究可能提示，糖尿病患者脑干诱发电位异常是由糖尿病大血管病变或微血管病变所致。
