Iriarte J, de Castro P, Zubieta J L, Artieda J
Departamento de Neurología, Clínica Universitaria de Navarra, Pamplona.
Neurologia. 1993 Jun-Jul;8(6):194-6.
Normal nerve impulse conduction through pathological areas has been documented but is believed to be rare in Multiple Sclerosis (MS). We present two patients with clinically definite Multiple Sclerosis, Poser's type 1a, in whom evoked potentials (EP) and magnetic resonance imaging (MRI) were performed for diagnostic purposes. The first patient had normal brainstem auditory evoked potentials (BAER) and normal somatosensory evoked potentials (SEP) despite a large unilateral midbrain lesion on MRI. The second patient had normal SEP and an extensive lesion in the cervical spinal cord. These findings demonstrate that normal transmission can occur through hyperintense areas, and the rise the problem of nature of the lesions in Multiple Sclerosis.
已有文献记载正常神经冲动可通过病理区域传导，但在多发性硬化症（MS）中这种情况被认为很少见。我们报告了两名临床确诊为波泽尔1a型多发性硬化症的患者，为诊断目的对其进行了诱发电位（EP）和磁共振成像（MRI）检查。第一名患者尽管MRI显示单侧中脑有一个大的病变，但脑干听觉诱发电位（BAER）和体感诱发电位（SEP）均正常。第二名患者SEP正常，但颈髓有广泛病变。这些发现表明正常传导可通过高强度区域发生，这也引发了多发性硬化症病变性质的问题。
