Bradley Cathy J, Dahman Bassam, Given Charles W
Department of Health Administration and Massey Cancer Center, Virginia Commonwealth University, Grant House, Richmond, VA 23298-0203, USA.
J Clin Oncol. 2008 Nov 1;26(31):5067-73. doi: 10.1200/JCO.2008.16.3071. Epub 2008 Sep 15.
This study compares non-small-cell lung cancer (NSCLC) treatments provided to older patients (age > or = 66 years) who are dually eligible for Medicare and Medicaid with treatments provided to similar patients who are insured by Medicare. We extend the analysis to include a comparison of survival rates between Medicare and dually eligible patients. Dual eligibility is associated with low socioeconomic status. However, Medicaid coverage in addition to Medicare removes many financial barriers to care.
The sample included 2,626 older patients with local and regional stage NSCLC diagnosed between 1997 and 2000. Four outcomes were studied: the likelihood of receiving resection, chemotherapy, radiation therapy, and survival (perioperative and longer-term). Logistic regression was used to predict the likelihood of treatment, and stratified and multivariate analyses were used to evaluate differences in survival.
Dually eligible patients were half as likely to undergo resection as Medicare patients (P < .001) and were more likely to receive radiation than Medicare patients. Stratified and multivariate analyses showed that surgically treated dually eligible patients had slightly inferior survival as compared with that of Medicare patients. Survival was equivalent among patients who did not undergo resection, regardless of insurance coverage.
Older dually eligible patients with NSCLC had a lower likelihood of undergoing resection despite controls for socioeconomic factors and comorbidities. However, if such patients were surgically treated, survival improved substantially, but it remained inferior to the survival of Medicare patients. Additional research is needed to understand why resection rates were substantially lower among dually eligible patients.
本研究比较了同时符合医疗保险和医疗补助条件的老年患者(年龄≥66岁)与仅参加医疗保险的类似患者所接受的非小细胞肺癌(NSCLC)治疗情况。我们进一步分析,比较了医疗保险患者与双重资格患者的生存率。双重资格与社会经济地位较低相关。然而,除医疗保险外的医疗补助覆盖消除了许多医疗保健的经济障碍。
样本包括1997年至2000年间诊断为局部和区域期NSCLC的2626名老年患者。研究了四个结果:接受手术切除、化疗、放疗的可能性以及生存率(围手术期和长期)。采用逻辑回归预测治疗可能性,分层分析和多变量分析用于评估生存率差异。
双重资格患者接受手术切除的可能性仅为医疗保险患者的一半(P <.001),且比医疗保险患者更有可能接受放疗。分层分析和多变量分析显示,接受手术治疗的双重资格患者的生存率略低于医疗保险患者。无论保险覆盖情况如何,未接受手术切除的患者生存率相当。
尽管对社会经济因素和合并症进行了控制,但同时符合资格的老年NSCLC患者接受手术切除的可能性较低。然而,如果这些患者接受手术治疗,生存率会大幅提高,但仍低于医疗保险患者。需要进一步研究以了解为什么双重资格患者的手术切除率大幅较低。