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色甘酸钠治疗期间的哮喘和荨麻疹。病例报告。

Asthma and urticaria during disodium cromoglycate treatment. A case report.

作者信息

Menon M P, Das A K

出版信息

Scand J Respir Dis. 1977 Jun;58(3):145-50.

PMID:18795
Abstract

A 10-year-old asthmatic boy began to suffer from urticarial rash and moderately severe bronchospasm after 8 weeks' treatment with disodium cromoglycate. Initially, DSCG had helped to control his asthmatic attacks, and steroid therapy could be discontinued. Inhalation provocation test with DSCG aerosol, 4 months after stopping DSCG treatment, showed an immediate-type 1 response and urticaria. A repeat provocation test, under antihistaminic cover , failed to produce similar response. When DSCG was withdrawn, urticaria vanished and the child remained symptom-free. Disodium cromoglycate is regarded as the possible aetiological agent.

摘要

一名10岁哮喘男孩在接受色甘酸钠治疗8周后开始出现荨麻疹皮疹和中度严重支气管痉挛。起初,色甘酸钠有助于控制他的哮喘发作,类固醇治疗可以停用。在停止色甘酸钠治疗4个月后,使用色甘酸钠气雾剂进行吸入激发试验,显示出速发型1型反应和荨麻疹。在抗组胺药覆盖下进行的重复激发试验未能产生类似反应。当停用色甘酸钠时,荨麻疹消失,孩子保持无症状。色甘酸钠被认为是可能的病因。

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Bronchodilator effect of sodium cromoglycate and its clinical implications.色甘酸钠的支气管扩张作用及其临床意义。
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