Züchner Tina, Failla Antonio Virgilio, Steiner Mathias, Meixner Alfred J
Institute of Physical and Theoretical Chemistry, Tübingen University, Auf der Morgenstelle8, 72076 Tübingen, Germany.
Opt Express. 2008 Sep 15;16(19):14635-44. doi: 10.1364/oe.16.014635.
We study spatially isolated, individual gold nanorods placed at a planar interface between two dielectric media using confocal interference scattering microscopy in combination with higher order laser modes. Approaching refractive index matching conditions, we observe that the elastic scattering patterns of individual nanorods exhibit an exponential increase of both the scattering intensity and the signal-to-background ratio. In case refractive index matching conditions are fullfilled, the data acquisition rates are maximized and suitable for in-vivo biological measurements. In all cases, the characteristic two-lobe shape of the scattering patterns of single nanorods remains unchanged while the sign of the image contrast is a direct consequence of the refractive index variation occurring at the interface.
我们使用共焦干涉散射显微镜结合高阶激光模式，研究了置于两种介电介质平面界面处的空间隔离的单个金纳米棒。接近折射率匹配条件时，我们观察到单个纳米棒的弹性散射图案呈现出散射强度和信噪比的指数增长。在满足折射率匹配条件的情况下，数据采集速率最大化，适用于体内生物学测量。在所有情况下，单个纳米棒散射图案的特征双叶形状保持不变，而图像对比度的符号是界面处发生的折射率变化的直接结果。
