培养的血管内皮和淋巴管内皮的比较研究

A comparative study of cultured vascular and lymphatic endothelium.

作者信息

Yong L C, Jones B E

机构信息

School of Pathology, University of New South Wales, Australia.

出版信息

Exp Pathol. 1991;42(1):11-25. doi: 10.1016/s0232-1513(11)80030-7.

DOI:10.1016/s0232-1513(11)80030-7

PMID:1879509

Abstract

There is comparatively little knowledge of the structure and function of cultured lymphatic endothelium. A study was carried out to compare the intrinsic growth characteristics of cultured lymphatic endothelial cells with cultured endothelial derived from blood vessels. It was found that cultured lymphatic endothelium has growth requirements and growth characteristics similar to vascular endothelium. It also possesses FVIIIRA and Weibel-Palade bodies for specific identification. The results of this study have provided important base line data for subsequent studies of the pathobiology of lymphatic endothelium.

摘要

目前对于培养的淋巴管内皮细胞的结构和功能了解相对较少。开展了一项研究，以比较培养的淋巴管内皮细胞与培养的血管来源内皮细胞的内在生长特性。研究发现，培养的淋巴管内皮细胞具有与血管内皮细胞相似的生长需求和生长特性。它还拥有用于特异性识别的因子VIII相关抗原（FVIIIRA）和魏尔-帕拉德小体（Weibel-Palade bodies）。这项研究的结果为后续淋巴管内皮细胞病理生物学研究提供了重要的基线数据。