Habek Mario, Supe Svjetlana, Poljaković Zdravka, Gelpi Ellen, Alesch François, Ozretić David, Brinar Vesna V
University Department of Neurology, Zagreb School of Medicine and University Hospital Center, Zagreb, Croatia.
J Neurol Sci. 2008 Dec 15;275(1-2):167-9. doi: 10.1016/j.jns.2008.07.036. Epub 2008 Sep 16.
We present a patient who developed progressive neurological disease caused by lesions histologically compatible with those observed in subacute brainstem angioencephalopathy. The patient was treated with low-molecular weight heparin, and treatment response was monitored clinically and with MRI. Anticoagulation therapy stopped progression of the neurological deficit and led to improvement of MRI findings. This report further supports the existence of subacute brainstem angioencephalopathy as a characteristic disease entity and gives insight into possible therapeutic approach with anticoagulation treatment.
我们报告了一名患者，其出现了由组织学上与亚急性脑干血管性脑病中观察到的病变相符的病变所引起的进行性神经疾病。该患者接受了低分子量肝素治疗，并通过临床和MRI监测治疗反应。抗凝治疗阻止了神经功能缺损的进展，并使MRI表现得到改善。本报告进一步支持了亚急性脑干血管性脑病作为一种特征性疾病实体的存在，并深入探讨了抗凝治疗可能的治疗方法。
