TESE：生成特定蛋白质结构测试集合集。
TESE: generating specific protein structure test set ensembles.
作者信息
Sirocco Francesco, Tosatto Silvio C E
机构信息
Department of Biology, University of Padova, Viale G. Colombo 3, 35131 Padova, Italy.
出版信息
Bioinformatics. 2008 Nov 15;24(22):2632-3. doi: 10.1093/bioinformatics/btn488. Epub 2008 Sep 16.
UNLABELLED
TESE is a web server for the generation of test sets of protein sequences and structures fulfilling a number of different criteria. At least three different use cases can be envisaged: (i) benchmarking of novel methods; (ii) test sets tailored for special needs and (iii) extending available datasets. The CATH structure classification is used to control structural/sequence redundancy and a variety of structural quality parameters can be used to interactively select protein subsets with specific characteristics, e.g. all X-ray structures of alpha-helical repeat proteins with more than 120 residues and resolution <2.0 A. The output includes FASTA-formatted sequences, PDB files and a clickable HTML index file containing images of the selected proteins. Multiple subsets for cross-validation are also supported.
AVAILABILITY
The TESE server is available for non-commercial use at URL: http://protein.bio.unipd.it/tese/.
未标注
TESE是一个网络服务器，用于生成满足多种不同标准的蛋白质序列和结构测试集。至少可以设想三种不同的用例：（i）新方法的基准测试；（ii）针对特殊需求定制的测试集；（iii）扩展现有数据集。CATH结构分类用于控制结构/序列冗余，并且可以使用各种结构质量参数来交互式选择具有特定特征的蛋白质子集，例如，具有超过120个残基且分辨率<2.0 Å的α-螺旋重复蛋白的所有X射线结构。输出包括FASTA格式的序列、PDB文件以及一个包含所选蛋白质图像的可点击HTML索引文件。还支持用于交叉验证的多个子集。
可用性
TESE服务器可在以下网址供非商业使用：http://protein.bio.unipd.it/tese/ 。
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