Costa André Nathan, Mendes Daniel Melo, Toufen Carlos, Arrunátegui Gino, Caruso Pedro, de Carvalho Carlos Roberto Ribeiro
Department of Pulmonology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brasil.
J Bras Pneumol. 2008 Aug;34(8):622-5. doi: 10.1590/s1806-37132008000800013.
Fat embolism is defined as mechanical blockage of the vascular lumen by circulating fat globules. Although it primarily affects the lungs, it can also affect the central nervous system, retina, and skin. Fat embolism syndrome is a dysfunction of these organs caused by fat emboli. The most common causes of fat embolism and fat embolism syndrome are long bone fractures, although there are reports of its occurrence after cosmetic procedures. The diagnosis is made clinically, and treatment is still restricted to support measures. We report the case of a female patient who developed adult respiratory distress syndrome due to fat embolism in the postoperative period following liposuction and fat grafting. In this case, the patient responded well to alveolar recruitment maneuvers and protective mechanical ventilation. In addition, we present an epidemiological and pathophysiological analysis of fat embolism syndrome after cosmetic procedures.
脂肪栓塞被定义为循环中的脂肪球对血管腔的机械性阻塞。尽管它主要影响肺部，但也可影响中枢神经系统、视网膜和皮肤。脂肪栓塞综合征是由脂肪栓子引起的这些器官的功能障碍。脂肪栓塞和脂肪栓塞综合征最常见的原因是长骨骨折，不过也有其在美容手术后发生的报道。诊断依靠临床做出，治疗仍限于支持措施。我们报告一例女性患者，她在抽脂和脂肪移植术后因脂肪栓塞发生了成人呼吸窘迫综合征。在该病例中，患者对肺泡复张手法和保护性机械通气反应良好。此外，我们还对美容手术后的脂肪栓塞综合征进行了流行病学和病理生理学分析。
