Nenonen J, Purcell C J, Horacek B M, Stroink G, Katila T
Department of Technical Physics, Helsinki University of Technology, Espoo, Finland.
IEEE Trans Biomed Eng. 1991 Jul;38(7):658-64. doi: 10.1109/10.83565.
We describe a fast and numerically effective biomagnetic inverse solution using a moving dipole in a realistic homogeneous torso. We applied the localization model and high-resolution magnetocardiographic mapping to localize noninvasively the ventricular preexcitation site in ten patients suffering from Wolff-Parkinson-White syndrome. In all cases, the computed localization results were compared to the results obtained by invasive catheter technique. Using a standard-size torso model in all cases, the average 3-D distance between the computed noninvasive locations and the invasively obtained results was 2.8 +/- 1.4 cm. When the torso was rescaled to better match the true shape of the subject in five cases, the 3-D average was improved to 2.2 +/- 1.0 cm. This accuracy is very satisfactory, suggesting that the method would be clinically useful.
我们描述了一种在逼真的均匀躯干模型中使用移动偶极子的快速且数值有效的生物磁逆解。我们应用定位模型和高分辨率心磁图映射对10例患有预激综合征的患者进行无创心室预激部位定位。在所有病例中，将计算得出的定位结果与通过有创导管技术获得的结果进行比较。在所有病例中均使用标准尺寸的躯干模型，计算得出的无创定位与有创获得的结果之间的三维平均距离为2.8±1.4厘米。在5例病例中，当躯干重新缩放以更好地匹配受试者的真实形状时，三维平均值提高到2.2±1.0厘米。这种准确性非常令人满意，表明该方法在临床上将是有用的。
