Taylor W J, Colvine K, Gregory K, Collis J, McQueen F M, Dalbeth N
Department of Medicine, University of Otago, Wellington, New Zealand.
Clin Exp Rheumatol. 2008 Jul-Aug;26(4):620-6.
There are no disability instruments that have specifically been validated for gout. The aim of this study was to determine the construct validity of the Health Assessment Questionnaire Disability Index (HAQ-DI) in gout and the internal validity using Rasch analysis.
An observational cohort study of two groups of clinic patients with gout (n=20, n=53), in which clinical and functional measures were correlated with HAQ-DI scores. Rasch analysis was used to determine the internal validity of summated scores as a measure of physical disability.
The HAQ-DI items fitted a Rasch measurement model, confirming internal validity of the scale, although there was evidence of disordered thresholds and rescoring items as a 3-option response rather than a 4-option response improved model fit and resolved the disordered thresholds. HAQ-DI scores showed a bimodal distribution and evidence of floor effects. Clinical indices correlated highly with HAQ-DI scores in gout patients, particularly other measures of physical function. A strong relationship between days of sick leave and HAQ-DI was observed in gout patients (r2=0.44, p<0.001).
It is concluded that HAQ-DI has good construct and internal validity in gout but a modified scoring approach better fits a Rasch model.
目前尚无专门针对痛风进行验证的残疾评估工具。本研究旨在确定健康评估问卷残疾指数(HAQ-DI)在痛风患者中的结构效度,并使用拉施分析确定其内部效度。
对两组门诊痛风患者(n = 20,n = 53)进行观察性队列研究,将临床和功能指标与HAQ-DI评分进行相关性分析。采用拉施分析确定总分作为身体残疾衡量指标的内部效度。
HAQ-DI项目符合拉施测量模型,证实了该量表的内部效度,尽管有证据表明存在阈值紊乱,将项目重新评分改为三选项回答而非四选项回答可改善模型拟合并解决阈值紊乱问题。HAQ-DI评分呈双峰分布且存在地板效应。痛风患者的临床指标与HAQ-DI评分高度相关,尤其是其他身体功能指标。痛风患者的病假天数与HAQ-DI之间存在强相关性(r2 = 0.44,p < 0.001)。
得出结论,HAQ-DI在痛风患者中具有良好的结构效度和内部效度,但改良的评分方法更符合拉施模型。