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痛风患者功能障碍测量指标的比较。

Comparison of measures of functional disability in patients with gout.

机构信息

Institute for Behavioural Research, Faculty of Behavioural Sciences, University of Twente, The Netherlands.

出版信息

Rheumatology (Oxford). 2011 Apr;50(4):709-13. doi: 10.1093/rheumatology/keq387. Epub 2010 Dec 2.

DOI:10.1093/rheumatology/keq387
PMID:21131272
Abstract

OBJECTIVE

To compare the measurement properties of the HAQ disability index (HAQ-DI), HAQ-II and short form 36 physical functioning scale (PF-10) in patients with gout.

METHODS

A cross-sectional sample of 97 patients with gout completed all three measures. Reliability was assessed by examining the internal consistency of the scales. Validity was assessed by testing for expected intercorrelations and associations with other aspects of health status and the ability to discriminate between patients with different levels of general health. Additionally, distributional properties were examined.

RESULTS

All three measures demonstrated high reliability (Cronbach's α ≥ 0.93), strong intercorrelations (r  ≥  0.75), and the expected pattern of external correlations. The HAQ-DI and HAQ-II performed somewhat better in discriminating between patients. However, both demonstrated ceiling effects of 34.0 and 25.8%, respectively, compared with only 7.2% of the patients scoring no disability on the PF-10.

CONCLUSIONS

The HAQ-DI, HAQ-II and PF-10 demonstrated similar and adequate reliability and validity for measuring functional disability in patients with gout. The large ceiling effects of both HAQ versions, however, may point to limited content validity and responsiveness to change. Further research should examine whether current instruments cover all aspects of physical functioning relevant to patients with gout.

摘要

目的

比较痛风患者的健康评估问卷残疾指数(HAQ-DI)、HAQ-II 和简化 36 健康调查量表躯体功能评分(PF-10)的测量特性。

方法

横断面样本 97 例痛风患者完成了所有三种测量方法。通过检查量表的内部一致性来评估可靠性。通过测试预期的相关性和与健康状况的其他方面的关联以及区分不同一般健康水平的患者的能力来评估有效性。此外,还检查了分布特性。

结果

所有三种方法的可靠性均较高(克朗巴赫α≥0.93),相关性较强(r≥0.75),且外部相关性的预期模式一致。HAQ-DI 和 HAQ-II 在区分患者方面的表现稍好。然而,与 PF-10 评分无残疾的患者比例仅为 7.2%相比,HAQ-DI 和 HAQ-II 分别分别有 34.0%和 25.8%的患者存在天花板效应。

结论

HAQ-DI、HAQ-II 和 PF-10 用于测量痛风患者的功能残疾,具有相似且足够的可靠性和有效性。然而,这两种 HAQ 版本的天花板效应较大,可能表明其内容有效性和对变化的反应性有限。进一步的研究应检验当前的工具是否涵盖了痛风患者躯体功能的所有相关方面。

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