Clark Michael R, Stoller Kenneth B, Brooner Robert K
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA.
Can J Psychiatry. 2008 Aug;53(8):496-508. doi: 10.1177/070674370805300804.
To review the problem of chronic pain in patients with substance use disorders, focusing on the prevalence of chronic pain in patients with substance dependence disorders, especially prescription opioid dependence, associated comorbidities, and the impact on drug abuse treatment response.
We identified relevant articles using PubMed from 1987 to 2008. Additional articles were obtained from the reference lists of key reviews of relevant topics. Studies were included if they investigated the relation between chronic pain and substance use disorders. Of particular interest were articles that proposed integrated treatment for both problems.
The high prevalence of chronic pain syndromes was only recently explored in patients seeking treatment for drug abuse. The presence of chronic pain increases the risk of poor response to substance abuse treatment and an increased likelihood of multiple comorbidities that further add to the negative impact experienced by patients with substance dependence disorders. Substance abuse treatment programs offering integrated medical and psychiatric care for these comorbidities improve outcomes, with stepped care approaches offering the best treatment by tailoring the level of care to the individual patient's needs.
Substance abuse treatment programs should expand their services to address the comorbidities likely to pose barriers to successful drug rehabilitation. Given the high prevalence and negative impact of chronic pain, new pain management services should be integrated within the drug treatment program and adapted as patients demonstrate the need for more intensive treatment. If applied to the problem of chronic pain, a model substance abuse treatment program of integrated stepped care would improve outcomes for patients with both devastating disorders.
回顾物质使用障碍患者的慢性疼痛问题,重点关注物质依赖障碍患者,尤其是处方阿片类药物依赖患者的慢性疼痛患病率、相关合并症以及对药物滥用治疗反应的影响。
我们使用PubMed检索了1987年至2008年的相关文章。从相关主题的关键综述的参考文献列表中获取了其他文章。如果研究调查了慢性疼痛与物质使用障碍之间的关系,则纳入该研究。特别感兴趣的是那些提出针对这两个问题进行综合治疗的文章。
直到最近才在寻求药物滥用治疗的患者中探讨慢性疼痛综合征的高患病率。慢性疼痛的存在增加了对物质滥用治疗反应不佳的风险,并且增加了多种合并症的可能性,这进一步加剧了物质依赖障碍患者所经历的负面影响。为这些合并症提供综合医疗和精神护理的物质滥用治疗项目可改善治疗效果,逐步护理方法通过根据个体患者的需求调整护理水平提供最佳治疗。
物质滥用治疗项目应扩大其服务范围,以解决可能对成功戒毒构成障碍的合并症。鉴于慢性疼痛的高患病率和负面影响,应在药物治疗项目中整合新的疼痛管理服务,并根据患者对更强化治疗的需求进行调整。如果应用于慢性疼痛问题,综合逐步护理的典型物质滥用治疗项目将改善这两种破坏性疾病患者的治疗效果。