• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

糖尿病足伤口的生物学基础。

Biological basis of diabetic foot wounds.

作者信息

Clemens Mark W, Attinger Chris E

机构信息

Department of Plastic Surgery, Georgetown University Medical Center, Washington, D.C. USA.

出版信息

Surg Technol Int. 2008;17:89-95.

PMID:18802887
Abstract

The steps to achieving a healthy healing wound include a correct diagnosis, ensuring a good local blood supply, debriding the wound to reveal a clean base, correcting the biomechanical abnormality, and nurturing the wound until it shows signs of healing. Debridement should be performed as often as necessary until the wound is deemed clean and ready for reconstruction. The repair is then dictated by how much of the foot remains post-debridement and how the foot can be closed in the most biomechanically stable construct possible. The subsequent reconstruction can then usually be accomplished by simple techniques most of the time, and with complex flap reconstruction in about 10% of cases. Wound healing adjuncts such as growth factor, cultured skin, and hyperbaric oxygen can be helpful adjuncts.

摘要

实现伤口健康愈合的步骤包括正确诊断、确保良好的局部血液供应、清创伤口以露出清洁的基底、纠正生物力学异常以及护理伤口直至其显示出愈合迹象。应根据需要尽可能频繁地进行清创,直到伤口被认为清洁且准备好进行重建。然后,修复方式取决于清创后足部剩余的部分以及如何以最生物力学稳定的结构闭合足部。随后的重建通常在大多数情况下可通过简单技术完成,约10%的病例需要复杂的皮瓣重建。伤口愈合辅助手段,如生长因子、培养皮肤和高压氧,可能是有用的辅助方法。

相似文献

1
Biological basis of diabetic foot wounds.糖尿病足伤口的生物学基础。
Surg Technol Int. 2008;17:89-95.
2
Innovation and management of diabetic foot wounds.糖尿病足伤口的创新与管理。
Surg Technol Int. 2010 Oct;20:61-71.
3
Healing diabetic foot ulcers using cortical bone fenestration and cell therapy.
Surg Technol Int. 2008;17:85-8.
4
Wound-healing protocols for diabetic foot and pressure ulcers.糖尿病足和压疮的伤口愈合方案。
Surg Technol Int. 2003;11:85-92.
5
Wound healing. New modalities for a new millennium.伤口愈合。新千年的新模式。
Clin Podiatr Med Surg. 1998 Jan;15(1):117-28.
6
Mechanical adjuncts to wound healing.
Curr Surg. 2005 Sep-Oct;62(5):465-9. doi: 10.1016/j.cursur.2004.11.024.
7
Surgical débridement. The key to successful wound healing and reconstruction.手术清创术。伤口成功愈合与重建的关键。
Clin Podiatr Med Surg. 2000 Oct;17(4):599-630.
8
Bioengineered alternative tissues and hyperbaric oxygen in lower extremity wound healing.生物工程替代组织与高压氧在下肢伤口愈合中的应用
Clin Podiatr Med Surg. 2007 Jul;24(3):529-46, x. doi: 10.1016/j.cpm.2007.03.011.
9
Advances in the treatment of the diabetic foot: Is there a role for adjunctive hyperbaric oxygen therapy?糖尿病足治疗的进展:辅助高压氧治疗是否有作用?
Wound Repair Regen. 2004 Jan-Feb;12(1):2-10. doi: 10.1111/j.1067-1927.2004.012104.x.
10
Effect of hyperbaric oxygen therapy on healing of diabetic foot ulcers.高压氧疗法对糖尿病足溃疡愈合的影响。
J Foot Ankle Surg. 2008 Nov-Dec;47(6):515-9. doi: 10.1053/j.jfas.2008.08.002. Epub 2008 Sep 16.

引用本文的文献

1
Adipose stromal cells repair pressure ulcers in both young and elderly mice: potential role of adipogenesis in skin repair.脂肪基质细胞修复年轻和老年小鼠的压力性溃疡:脂肪生成在皮肤修复中的潜在作用。
Stem Cells Transl Med. 2015 Jun;4(6):632-42. doi: 10.5966/sctm.2014-0235. Epub 2015 Apr 21.