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有限元在腰椎退行性椎间盘疾病治疗的植入物研究中的应用。

Finite element application in implant research for treatment of lumbar degenerative disc disease.

作者信息

Zhang Qing Hang, Teo Ee Chon

机构信息

School of Mechanical and Aerospace Engineering, 50 Nanyang Ave, Nanyang Technological University, 639798 Singapore, Singapore.

出版信息

Med Eng Phys. 2008 Dec;30(10):1246-56. doi: 10.1016/j.medengphy.2008.07.012. Epub 2008 Sep 18.

DOI:10.1016/j.medengphy.2008.07.012
PMID:18804398
Abstract

Surgical treatment for disc degeneration can be roughly grouped as fusion, disc replacement and dynamic stabilization. The clinical efficacy and biomechanical features of the implants used for disc degenerations can be evaluated through short- or long-term follow up observation, in vitro and in vivo experiments and computational simulations. Finite element models are already making an important contribution to our understanding of the spine and its components. Models are being used to reveal the biomechanical function of the spine and its behavior when healthy, diseased or damaged. They are also providing support in the design and application of spinal instrumentation. The article reviewed the most recent studies in the application of FE models that address the issue of implant research for treatment of low back pain. The published studies were grouped and reviewed thoroughly based on the function of implants investigated. The considerations of the finite element analysis in these studies were further discussed.

摘要

椎间盘退变的外科治疗方法大致可分为融合术、椎间盘置换术和动态稳定术。用于椎间盘退变的植入物的临床疗效和生物力学特性可通过短期或长期随访观察、体外和体内实验以及计算模拟来评估。有限元模型已经在我们对脊柱及其组成部分的理解方面做出了重要贡献。模型被用于揭示脊柱在健康、患病或受损时的生物力学功能及其行为。它们还为脊柱器械的设计和应用提供支持。本文回顾了有限元模型在治疗腰痛植入物研究方面的最新应用研究。根据所研究植入物的功能对已发表的研究进行了分组并进行了全面回顾。进一步讨论了这些研究中有限元分析的考量因素。

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