Stone Wendy L, McMahon Caitlin R, Henderson Lynnette M
Vanderbilt University, USA.
Autism. 2008 Sep;12(5):557-73. doi: 10.1177/1362361308096403.
The study examined the properties of the Screening Tool for Autism in Two-Year-Olds (STAT) for children under 24 months. The STAT provides a standard context for observing social-communicative behavior in play, imitation, and communication. Seventy-one children received the STAT between 12 and 23 months of age and a follow-up diagnostic evaluation after 24 months. All had an older sibling with an autism spectrum diagnosis (n=59) or had been referred for evaluation for concerns about autism (n=12). Signal detection analysis resulted in a cut score of 2.75 for this sample, which yielded a sensitivity of 0.95, specificity of 0.73, positive predictive value of 0.56, and negative predictive value of 0.97. False positives were highest for the 12- to 13-month-old age group; STAT screening properties were improved when the sample was limited to children 14 months and older. Implications for using the STAT with children under 24 months are discussed.
该研究考察了针对24个月以下儿童的《两岁儿童自闭症筛查工具》(STAT)的特性。STAT为观察游戏、模仿和交流中的社交沟通行为提供了一个标准情境。71名儿童在12至23个月大时接受了STAT测试,并在24个月后接受了后续诊断评估。所有儿童均有一名被诊断为自闭症谱系障碍的哥哥或姐姐(n = 59),或者因家长担心自闭症而被转介进行评估(n = 12)。信号检测分析得出该样本的临界分数为2.75,其灵敏度为0.95,特异度为0.73,阳性预测值为0.56,阴性预测值为0.97。12至13个月大的年龄组假阳性率最高;当样本仅限于14个月及以上的儿童时,STAT的筛查特性有所改善。文中讨论了在24个月以下儿童中使用STAT的意义。