DivIVA聚集体标记了天蓝色链霉菌中菌丝分支的位点，并能建立新的细胞壁生长区域。
Assemblies of DivIVA mark sites for hyphal branching and can establish new zones of cell wall growth in Streptomyces coelicolor.
作者信息
Hempel Antje Marie, Wang Sheng-bing, Letek Michal, Gil José A, Flärdh Klas
机构信息
Department of Cell and Organism Biology, Lund University, Sölvegatan 35, 223 62 Lund, Sweden.
出版信息
J Bacteriol. 2008 Nov;190(22):7579-83. doi: 10.1128/JB.00839-08. Epub 2008 Sep 19.
Abstract
Time-lapse imaging of Streptomyces hyphae revealed foci of the essential protein DivIVA at sites where lateral branches will emerge. Overexpression experiments showed that DivIVA foci can trigger establishment of new zones of cell wall assembly, suggesting a key role of DivIVA in directing peptidoglycan synthesis and cell shape in Streptomyces.
摘要
对链霉菌菌丝的延时成像显示，必需蛋白DivIVA的聚集点出现在侧枝将要出现的位置。过表达实验表明，DivIVA聚集点可触发新的细胞壁组装区域的形成，这表明DivIVA在指导链霉菌的肽聚糖合成和细胞形态方面发挥关键作用。
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