Suppr超能文献

[人乳头瘤病毒(HPV)阳性女性生殖道中的脲原体是否会影响宫颈细胞学异常?]

[May ureaplasmas in genital tract of HPV-positive women influence abnormal cytology of cervix?].

作者信息

Biernat-Sudolska Małgorzata, Szostek Sława, Rojek-Zakrzewska Danuta, Kopeć Jolanta, Zawilińska Barbara

机构信息

Zakład Wirusologii, Katedra Mikrobiologii CM UJ, Kraków.

出版信息

Przegl Epidemiol. 2008;62(2):447-52.

Abstract

The aim of the study was to estimate the incidence of Ureaplasma urealyticum (U.u.) and Ureaplasma parvum (Up.) in 168 women diagnosed with LSIL infected and not infected with HPV vs. 82 women with no cytological abnormalities in the cervix (control group). The material used in the study were cervical secretions samples. PCR was used to confirm the presence of HPV and to identify the species of ureaplasmas. U.p. was significantly more frequent in both groups of women. In the study group, ureaplasmas were more frequently isolated in the HPV infected (31%) vs. HPV negative (16%) women. No direct relationship was found between ureaplasmas and LSIL. Statistical analysis showed, that infection with HPV occurred more frequently in the presence of ureaplasmas (OR = 1.79; 95% PU 0.90-3.53; p = 0.093). The above relationship was most evident for U.u. The risk for HPV infection in that case was 6.5 fold higher. Infections with ureaplasmas, especially U.u should be considered as a factor increasing the risk of HPV infection of the cervical epithelial cells.

摘要

该研究的目的是评估168例诊断为低度鳞状上皮内病变(LSIL)且感染和未感染人乳头瘤病毒(HPV)的女性与82例宫颈细胞学无异常的女性(对照组)中解脲脲原体(U.u.)和微小脲原体(Up.)的发生率。研究使用的材料为宫颈分泌物样本。采用聚合酶链反应(PCR)来确认HPV的存在并鉴定脲原体的种类。Up.在两组女性中均更为常见。在研究组中,HPV感染女性(31%)比HPV阴性女性(16%)更频繁地分离出脲原体。未发现脲原体与LSIL之间存在直接关系。统计分析表明,在存在脲原体的情况下HPV感染更频繁发生(比值比[OR]=1.79;95%可信区间[PU]0.90 - 3.53;p = 0.093)。上述关系在U.u.中最为明显。在这种情况下HPV感染风险高6.5倍。脲原体感染,尤其是U.u.感染,应被视为增加宫颈上皮细胞HPV感染风险的一个因素。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验