Piwońska Marta, Szewczyk Adam
Laboratory of Intracellular Ion Channels, Biochemistry Department, Nencki Institute of Experimental Biology, 3 Pasteur St., 02-093 Warsaw, Poland.
Postepy Biochem. 2008;54(2):169-78.
Mitochondria play a key function in cellular metabolism. Additionally to ATP synthesis, mitochondria may buffor cytosolic calcium ions and generate reactive oxygen species. Due to these processes, mitochondria are involved in complex cytoprotective phenomena. Neuroprotection is very often based on changes in the integrity of mitochondrial membranes. In this report potential neuroprotective role of mitochondrial ion channels is discussed.
线粒体在细胞代谢中发挥关键作用。除了合成三磷酸腺苷（ATP）外，线粒体还可以缓冲胞质钙离子并产生活性氧。由于这些过程，线粒体参与了复杂的细胞保护现象。神经保护常常基于线粒体膜完整性的改变。在本报告中，将讨论线粒体离子通道潜在的神经保护作用。
