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静脉药物滥用者霉菌性股动脉假性动脉瘤的处理

The management of mycotic femoral pseudoaneurysms in intravenous drug abusers.

作者信息

Peirce Colin, Coffey J C, O'Grady Helen, Aly Sayed, O'Malley Kevin, O'Donohoe Martin

机构信息

Department of Vascular Surgery, Mater Misericordiae University Hospital, Dublin, Republic of Ireland.

出版信息

Ann Vasc Surg. 2009 May-Jun;23(3):345-9. doi: 10.1016/j.avsg.2008.08.013. Epub 2008 Sep 21.

Abstract

Mycotic femoral pseudoaneurysms, particularly in the drug-abusing population, pose a difficult problem to the vascular surgeon. Management ranges from ligation with debridement to extra-anatomical bypass. This study reviewed the management of mycotic femoral pseudoaneurysms presenting in intravenous drug abusers to an inner city tertiary referral center. Between 2001 and 2006, 11 cases presenting in nine patients were treated. The mean age was 30.7 years with a male-to-female ratio of 1:2. Eight patients had a positive viral status for the human immunodeficiency virus and/or hepatitis C. Two patients re-presented with a contralateral pseudoaneurysm. A combination of groin pain and swelling was the most common presentation. Two patients presented with significant hemorrhage. The diagnosis was confirmed by ultrasound in the majority of cases. Nine cases were managed with arterial ligation and debridement of the necrotic tissue. The two remaining cases were managed with ultrasound-guided thrombin injection and arterial puncture closure. On follow-up, one patient required a below-knee amputation following reinjection into the postoperative wound site. One further patient underwent a fifth metatarsal amputation due to ischemia. Ligation and debridement are well tolerated in the majority of drug-abusing patients diagnosed with mycotic femoral pseudoaneurysms.

摘要

霉菌性股部假性动脉瘤,尤其是在药物滥用人群中,给血管外科医生带来了难题。治疗方法从结扎清创到解剖外旁路手术不等。本研究回顾了静脉药物滥用者出现霉菌性股部假性动脉瘤后转诊至市中心三级转诊中心的治疗情况。2001年至2006年间,对9例患者中的11例进行了治疗。平均年龄为30.7岁,男女比例为1:2。8例患者人类免疫缺陷病毒和/或丙型肝炎病毒检测呈阳性。2例患者对侧出现假性动脉瘤。腹股沟疼痛和肿胀是最常见的表现。2例患者出现大量出血。大多数病例通过超声确诊。9例采用动脉结扎和坏死组织清创治疗。其余2例采用超声引导下凝血酶注射和动脉穿刺闭合治疗。随访中,1例患者术后伤口部位再次注射后需要进行膝下截肢。另1例患者因缺血接受了第五跖骨截肢。对于大多数诊断为霉菌性股部假性动脉瘤的药物滥用患者,结扎和清创耐受性良好。

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