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因自我注射导致霉菌性股总动脉假性动脉瘤的静脉吸毒者人口统计学变化并不影响急诊结扎后的结局。

Changes in the demographics of intravenous drug users with mycotic common femoral artery pseudoaneurysm as a consequence of self-injection does not influence outcome following emergency ligation.

作者信息

Stevenson Richard P, Semple Catriona, Hussey Keith, McGovern Josh, Stuart Wesley P, Kingsmore David B

机构信息

1 Department of Vascular Surgery, Queen Elizabeth University Hospital, UK.

2 Department of Vascular Surgery, Raigmore Hospital, UK.

出版信息

Vascular. 2017 Oct;25(5):520-524. doi: 10.1177/1708538117700763. Epub 2017 Mar 30.

DOI:10.1177/1708538117700763
PMID:28358245
Abstract

Objectives The reported annual incidence of mycotic pseudoaneurysm of the common femoral artery in intravenous drug users has been estimated at 0.03%. Over the past 5 years in Scotland, the proportion of people receiving specialist attention for heroin use over the age of 40 years has increased from 15 to 22%. Although routinely managed with arterial ligation (without reconstruction), some series have reported rates of major limb amputation of up to 10%. We sought to define whether this management strategy was still acceptable in an older population. Methods Retrospective review of patients presenting to a tertiary vascular service with mycotic pseudoaneurysm of the common femoral artery due to arterial injection by intravenous drug users between October 2010 and March 2016. Variables of interest included patient demographics and requirement for major amputation. Results There were 55 patients identified. The annual incidence of mycotic pseudoaneurysm of the common femoral artery in intravenous drug users was 2.1%. It was more common in men (3:1) and the mean age at presentation was 41 years (standard deviation ± 8 years). Three patients underwent major limb amputation during the index admission for severe limb ischaemia (two transfemoral amputations; one hip-disarticulation). Following discharge two patients were readmitted (134 and 200 days, respectively, following primary ligation) for major limb amputation due to of critical limb ischaemia. Conclusions Despite the increasing age of intravenous drug users presenting with mycotic pseudoaneurysm of the common femoral artery primary ligation of pseudoaneurysm would seem to remain an appropriate therapeutic intervention.

摘要

目的 据报道,静脉吸毒者股总动脉霉菌性假性动脉瘤的年发病率估计为0.03%。在过去5年中,苏格兰40岁以上因使用海洛因而接受专科治疗的人群比例从15%上升至22%。尽管通常采用动脉结扎术(不进行重建)进行治疗,但一些系列报道称,大肢体截肢率高达10%。我们试图确定这种治疗策略在老年人群中是否仍然可以接受。方法 回顾性分析2010年10月至2016年3月期间因静脉吸毒导致股总动脉霉菌性假性动脉瘤而就诊于三级血管服务机构的患者。感兴趣的变量包括患者人口统计学特征和大截肢需求。结果 共识别出55例患者。静脉吸毒者股总动脉霉菌性假性动脉瘤的年发病率为2.1%。男性更为常见(3:1),就诊时的平均年龄为41岁(标准差±8岁)。3例患者在首次住院期间因严重肢体缺血接受了大肢体截肢(2例经股截肢;1例髋关节离断)。出院后,2例患者(分别在初次结扎后134天和200天)因严重肢体缺血再次入院接受大肢体截肢。结论 尽管因股总动脉霉菌性假性动脉瘤就诊的静脉吸毒者年龄在增加,但假性动脉瘤的初次结扎似乎仍然是一种合适的治疗干预措施。

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