Bürgi H
Schweiz Med Wochenschr. 1976 Aug 21;106(34):1133-7.
Hormones act via receptors, i.e. structures which contain specific binding sites for any given hormone. The transmission of information is accomplished by reversible binding of the hormone to the receptor. Steroid hormones and triiodothyronine act via receptors which are located in the nucleus and regulate the biosynthesis of specific proteins. Peptide hormones and catecholamines combine with receptors within the cell membrane, thereby regulating the membrane-bound enzyme adenyle cyclase. The product of this enzyme, cyclic AMP, acts as a transmitter of the action of these hormones in the interior of the cell.
激素通过受体发挥作用，即含有特定激素结合位点的结构。信息传递是通过激素与受体的可逆性结合来完成的。类固醇激素和三碘甲状腺原氨酸通过位于细胞核内的受体发挥作用，并调节特定蛋白质的生物合成。肽类激素和儿茶酚胺与细胞膜内的受体结合，从而调节膜结合酶腺苷酸环化酶。这种酶的产物环磷酸腺苷在细胞内部充当这些激素作用的传递者。
