Mougeot-Martin M, Krulik M, Gintzburger S, Debray J
Sem Hop. 1976 Apr 9;52(14):883-8.
The authors report the case of a young 17 year-old girl with acute systemic lupus erythematosus who presented with purulent arthritis due to Group A hemolytic streptococcus in the knee, and perhaps other joints. She had not yet received any treatment. The purulent arthritis was cured by antibiotics. In spite of corticosteroids and immuno-suppressive agents (Chlorambucil), the patient died one year later. Spontaneous purulent arthritis is rare during systemic lupus erythematosus. We found only 8 other cases in the world literature. Contrary to our case, these were patients already treated with corticosteroid or immuno-suppressive agents. In our patient, the absence of previous treatment permitted us to incriminate the lupus itself in the onset of this infection. The conditions of onset of infection during lupus erythematosus are discussed.
作者报告了一例17岁年轻女性急性系统性红斑狼疮患者的病例，该患者因A组溶血性链球菌感染导致膝关节出现脓性关节炎，可能其他关节也有感染。她尚未接受任何治疗。脓性关节炎通过抗生素治愈。尽管使用了皮质类固醇和免疫抑制剂（苯丁酸氮芥），患者一年后仍死亡。系统性红斑狼疮期间自发性脓性关节炎很罕见。我们在世界文献中仅发现另外8例。与我们的病例不同，这些患者已经接受了皮质类固醇或免疫抑制剂治疗。在我们的患者中，由于之前未接受治疗，使我们能够将此次感染的发病归咎于狼疮本身。本文讨论了系统性红斑狼疮期间感染的发病情况。
