Coburn Natalie, Przybysz Raymond, Barbera Lisa, Hodgson David, Sharir Sharon, Laupacis Andreas, Law Calvin
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.
J Surg Oncol. 2008 Dec 1;98(7):490-9. doi: 10.1002/jso.21144.
To examine practice patterns and rates of computed tomography (CT), magnetic resonance imaging (MRI), and abdominal ultrasound (AUS) during staging, treatment and surveillance for cancer patients.
Using Ontario Health Insurance Plan billing data linked to the Ontario Cancer Registry, we determined rates of CT, MRI, and AUS by body site for breast, colorectal, lung, lymphoma, and prostate cancer, from 1998 to 2002. Rates of scans were additionally examined by region of patient residence and time from cancer diagnosis.
The frequency of imaging increased in nearly all scans and tumors over the study period. Rates of peri-diagnosis scans varied substantially by region, ranging from 1.7-fold variation (CT for lung cancer) to 50-fold variation (MRI for breast cancer). For breast cancer, there is possible over-utilization of CT, but overall rates of scanning appear reasonable for the other four cancers.
Considerable regional variation in imaging rates suggests utilization guidelines should be developed or knowledge transfer initiatives are needed to improve compliance to existing guidelines. In breast cancer, there appears to be over-utilization of imaging. Further studies are necessary to determine utilization for each stage, the reason scans were obtained, and the impact of scans on patient outcomes.
研究癌症患者在分期、治疗及监测期间计算机断层扫描(CT)、磁共振成像(MRI)和腹部超声(AUS)的应用模式及使用率。
利用与安大略癌症登记处相关联的安大略健康保险计划计费数据,我们确定了1998年至2002年期间乳腺癌、结直肠癌、肺癌、淋巴瘤和前列腺癌按身体部位划分的CT、MRI和AUS使用率。此外,还按患者居住地区和癌症诊断后的时间对扫描率进行了研究。
在研究期间,几乎所有扫描和肿瘤的成像频率均有所增加。诊断期间扫描率因地区而异,差异很大,从1.7倍(肺癌的CT)到50倍(乳腺癌的MRI)不等。对于乳腺癌,CT可能存在过度使用的情况,但其他四种癌症的总体扫描率似乎合理。
成像率存在显著的地区差异,这表明应制定使用指南,或者需要开展知识传播举措以提高对现有指南的遵循程度。在乳腺癌方面,似乎存在成像过度使用的情况。有必要进一步开展研究,以确定各阶段的使用情况、进行扫描的原因以及扫描对患者预后的影响。