Phifer C B, Ladd M D, Hall W G
Louisiana Scholars' College, Northwestern State University, Natchitoches 71497.
Physiol Behav. 1991 Apr;49(4):695-9. doi: 10.1016/0031-9384(91)90304-7.
The physiological stimulus for deprivation-enhanced ingestion was studied in developing rats. During an overnight deprivation period, continuous gastric infusions of isotonic saline or milk were made to 6- and 15-day-old rat pups in order to preferentially maintain hydrational or hydrational and nutritional status, respectively. Pups' ingestion was then studied in oral-infusion tests. In 6-day-old pups that received either milk or saline infusions, ingestion was depressed relative to intake in pups that were simply deprived. But in 15-day-old pups, only milk infusions reduced intake. These findings suggest that the increased ingestion stimulated by deprivation in pups less than a week of age results primarily from dehydration, and thus that nutrient-related feeding does not emerge until later in development.
在发育中的大鼠中研究了剥夺增强摄食的生理刺激因素。在过夜剥夺期间，分别对6日龄和15日龄的幼鼠持续胃内输注等渗盐水或牛奶，以分别优先维持水合状态或水合及营养状态。然后在口服输注试验中研究幼鼠的摄食情况。在接受牛奶或盐水输注的6日龄幼鼠中，与单纯剥夺的幼鼠相比，其摄食受到抑制。但在15日龄幼鼠中，只有牛奶输注会减少摄入量。这些发现表明，小于一周龄的幼鼠因剥夺而增加的摄食主要是由脱水引起的，因此与营养相关的进食直到发育后期才出现。
