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肾移植:使用磁共振尿路造影进行结构和功能评估

Kidney transplantation: structural and functional evaluation using MR Nephro-Urography.

作者信息

Kalb Bobby, Martin Diego R, Salman Khalil, Sharma Puneet, Votaw John, Larsen Christian

机构信息

Emory University School of Medicine, 1365 Clifton Road NE, Building A - AT622, Atlanta, Georgia 30322, USA.

出版信息

J Magn Reson Imaging. 2008 Oct;28(4):805-22. doi: 10.1002/jmri.21562.

Abstract

End-stage-renal disease (ESRD) is a major health issue in the United States, and the Medicare costs of ESRD totaled nearly USD 21 billion in 2005. Renal transplantation has emerged as the treatment of choice in this patient population, providing improved quality of life and lower healthcare costs compared with other treatment options. Imaging evaluation of a graft kidney plays a critical role in the postoperative care of the renal transplant patient. In the past, diagnostic evaluation of the transplant kidney has depended upon a combination of ultrasonography, computed tomography, MRI, and biopsy, used in conjunction with the patient's clinical presentation. However, new and developing advances in MR technology has lead to the development of MR Nephro-Urography (MRNU), which provides both anatomic and functional evaluation of the kidney in a single examination. It is expected that the increasing use of MRNU will have a significant impact on the management of renal transplant patients. This review describes MRNU methodology, examines known posttransplant complications, and highlights the utility of MRNU as a comprehensive imaging examination to diagnose both surgical and medical complications of the transplant kidney.

摘要

终末期肾病(ESRD)是美国的一个主要健康问题,2005年ESRD的医疗保险费用总计近210亿美元。肾移植已成为该患者群体的首选治疗方法,与其他治疗选择相比,它能提高生活质量并降低医疗成本。移植肾的影像学评估在肾移植患者的术后护理中起着关键作用。过去,移植肾的诊断评估依赖于超声检查、计算机断层扫描、磁共振成像(MRI)和活检的联合应用,并结合患者的临床表现。然而,磁共振技术的新进展和不断发展促使了磁共振肾尿路造影(MRNU)的出现,它能在一次检查中对肾脏进行解剖和功能评估。预计MRNU的使用增加将对肾移植患者的管理产生重大影响。本综述描述了MRNU方法,研究了已知的移植后并发症,并强调了MRNU作为一种综合影像学检查在诊断移植肾手术和医疗并发症方面的实用性。

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