Schindzielorz A, Edberg S C, Bia F J
Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn. 06510.
South Med J. 1991 Aug;84(8):1055-7. doi: 10.1097/00007611-199108000-00030.
Infections caused by Strongyloides stercoralis are not uncommon in the United States. Because of the many different manifestations of hyperinfection with this nematode, a high index of suspicion is essential, especially in immunocompromised patients, for whom such infections are frequently fatal. Patients originating from endemic areas and those who have traveled to such areas, even in the distant past, should have the possibility of strongyloidiasis evaluated before initiation of immunosuppressive therapy. Once considered, the diagnosis is not difficult and can be accomplished using readily available techniques and methods. Although thiabendazole has a high incidence of side effects and may not always eradicate infection, it remains the drug of choice for disseminated strongyloidiasis.
粪类圆线虫引起的感染在美国并不罕见。由于这种线虫超感染有许多不同表现,高度怀疑至关重要,尤其是在免疫功能低下的患者中,此类感染往往是致命的。来自流行地区的患者以及那些去过此类地区的人,即使是很久以前去过,在开始免疫抑制治疗前都应评估是否有粪类圆线虫病的可能。一旦考虑到,诊断并不困难,可通过现有技术和方法来完成。尽管噻苯达唑副作用发生率高且可能无法总是根除感染,但它仍是播散性粪类圆线虫病的首选药物。