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一名复发性多软骨炎患者出现粪类圆线虫高度感染及中枢神经系统受累

Strongyloides stercoralis hyperinfection and central nervous system involvement in a patient with relapsing polychondritis.

作者信息

Schindzielorz A, Edberg S C, Bia F J

机构信息

Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn. 06510.

出版信息

South Med J. 1991 Aug;84(8):1055-7. doi: 10.1097/00007611-199108000-00030.

DOI:10.1097/00007611-199108000-00030
PMID:1882264
Abstract

Infections caused by Strongyloides stercoralis are not uncommon in the United States. Because of the many different manifestations of hyperinfection with this nematode, a high index of suspicion is essential, especially in immunocompromised patients, for whom such infections are frequently fatal. Patients originating from endemic areas and those who have traveled to such areas, even in the distant past, should have the possibility of strongyloidiasis evaluated before initiation of immunosuppressive therapy. Once considered, the diagnosis is not difficult and can be accomplished using readily available techniques and methods. Although thiabendazole has a high incidence of side effects and may not always eradicate infection, it remains the drug of choice for disseminated strongyloidiasis.

摘要

粪类圆线虫引起的感染在美国并不罕见。由于这种线虫超感染有许多不同表现,高度怀疑至关重要,尤其是在免疫功能低下的患者中,此类感染往往是致命的。来自流行地区的患者以及那些去过此类地区的人,即使是很久以前去过,在开始免疫抑制治疗前都应评估是否有粪类圆线虫病的可能。一旦考虑到,诊断并不困难,可通过现有技术和方法来完成。尽管噻苯达唑副作用发生率高且可能无法总是根除感染,但它仍是播散性粪类圆线虫病的首选药物。

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Strongyloides stercoralis hyperinfection and central nervous system involvement in a patient with relapsing polychondritis.一名复发性多软骨炎患者出现粪类圆线虫高度感染及中枢神经系统受累
South Med J. 1991 Aug;84(8):1055-7. doi: 10.1097/00007611-199108000-00030.
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Case report: Antemortem diagnosis of central nervous system strongyloidiasis.病例报告:中枢神经系统类圆线虫病的生前诊断
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Opportunistic infections with Strongyloides stercoralis in renal transplantation.肾移植中粪类圆线虫引起的机会性感染。
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Strongyloides stercoralis infection complicating the central nervous system.粪类圆线虫感染并发中枢神经系统疾病。
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Disseminated Strongyloides stercoralis infection.播散性粪类圆线虫感染。
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Hyperinfection syndrome with Strongyloides stercoralis in malignant lymphoma.恶性淋巴瘤合并粪类圆线虫高感染综合征
Br Med J. 1973 Feb 3;1(5848):264-6. doi: 10.1136/bmj.1.5848.264.

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Rapid development of migratory, linear, and serpiginous lesions in association with immunosuppression.迅速发展的移行性、线状和匐行性皮损,伴有免疫抑制。
J Am Acad Dermatol. 2014 Jun;70(6):1130-4. doi: 10.1016/j.jaad.2013.11.036.
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Severe strongyloidiasis: a systematic review of case reports.
严重的类圆线虫病:病例报告的系统评价。
BMC Infect Dis. 2013 Feb 8;13:78. doi: 10.1186/1471-2334-13-78.
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A fatal case of systemic strongyloidiasis and review of the literature.一例系统性类圆线虫病致死病例及文献综述
Eur J Clin Microbiol Infect Dis. 1994 Dec;13(12):1069-74. doi: 10.1007/BF02111831.