Glik Amir, Masarwa Magdalena, Abuful Amin, Deeb Amar, Strugatsky Rosa, Farrer Lindsay A, Friedland Robert P, Inzelberg Rivka
Department of Neurology and The Sagol Neuroscience Center, Sheba Medical Center, Tel Hashomer, Israel.
Mov Disord. 2009 Jan 15;24(1):119-22. doi: 10.1002/mds.22324.
Essential tremor (ET) is much more prevalent than Parkinson's disease (PD) in Western countries. We estimated ET and PD prevalence in Wadi Ara Arabic villages in Northern Israel. In this door-to-door survey, all consenting residents aged >or=65 years were systematically examined by an Arabic speaking team. No prescreening questionnaires were used. A random sample of 900 subjects [437 males, mean age (SD) = 72.6 years (6.6)] of the 2,163 eligible residents were evaluated. Sixteen subjects had an action, intentional tremor. Tremor prevalence was estimated as 1.78% (95% CI 1.1-2.87). Nine of these had another likely cause of tremor. Only 7 patients were diagnosed as ET [prevalence 0.78% (95% CI 0.38-1.6)]. PD was diagnosed in 13 subjects. PD prevalence was 1.44% (95% CI 0.84-2.45). ET is unusually uncommon in this population and possibly even less frequent than PD. The PD prevalence in Wadi Ara is similar to that reported in Western countries.
在西方国家,特发性震颤(ET)比帕金森病(PD)更为常见。我们对以色列北部瓦迪阿拉阿拉伯村庄的特发性震颤和帕金森病患病率进行了估计。在这项挨家挨户的调查中,所有年龄≥65岁且同意参与的居民由一个讲阿拉伯语的团队进行系统检查。未使用预先筛选问卷。从2163名符合条件的居民中随机抽取了900名受试者[437名男性,平均年龄(标准差)=72.6岁(6.6)]进行评估。16名受试者存在动作性、意向性震颤。震颤患病率估计为1.78%(95%可信区间1.1 - 2.87)。其中9名有其他可能的震颤原因。只有7例患者被诊断为特发性震颤[患病率0.78%(95%可信区间0.38 - 1.6)]。13名受试者被诊断为帕金森病。帕金森病患病率为1.44%(95%可信区间0.84 - 2.45)。特发性震颤在该人群中异常罕见,甚至可能比帕金森病更不常见。瓦迪阿拉的帕金森病患病率与西方国家报道的相似。