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以色列瓦迪阿拉阿拉伯人群中帕金森病的患病率

The prevalence of Parkinson's disease in an Arab population, Wadi Ara, Israel.

作者信息

Masalha Rafik, Kordysh Ella, Alpert Gershon, Hallak Maher, Morad Mohammad, Mahajnah Muhammad, Farkas Peter, Herishanu Yuval

机构信息

Department of Neurology, Soroka University Medical Center, and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.

出版信息

Isr Med Assoc J. 2010 Jan;12(1):32-5.

Abstract

BACKGROUND

The prevalence of Parkinson's disease varies among ethnic and geographic groups around the world, being very low in China and high in Argentina. While the main etiology of the disease has yet to be determined, environmental, occupational and genetic factors seem to play important roles.

OBJECTIVES

To estimate the prevalence of PD in an Arab Muslim population in Israel, using the drug tracer approach.

METHODS

We studied a Muslim Arab population living in a well-defined geographic area in Israel, with the majority located in two towns and two large villages. Of the approximately 115,000 residents, about 38% are under the age of 15 and 7.75% are older than 65. Drug tracer methodology was applied in this study. All those who were on anti-PD medication were identified and examined by a neurologist to confirm the diagnosis.

RESULTS

The overall crude prevalence of PD in this population was low, 43.24/100,000, while the prevalence in the age group above 65 years was 477.32/100,000. Below this age, the prevalence was very low, 12.29/100,000. PD prevalence was higher in males than in females (ratio 1.17); 63% of male patients smoked cigarettes. The prevalence was found to be twice as high among the residents of rural areas, where most inhabitants work in agriculture.

CONCLUSIONS

The prevalence of PD among the Arab population in Israel is considered low and comparable to that reported in other Arab countries.

摘要

背景

帕金森病在世界各地不同种族和地理区域的患病率有所不同,在中国很低,在阿根廷则很高。虽然该疾病的主要病因尚未确定,但环境、职业和遗传因素似乎起着重要作用。

目的

采用药物追踪法估计以色列阿拉伯穆斯林人群中帕金森病的患病率。

方法

我们研究了居住在以色列一个明确地理区域的阿拉伯穆斯林人群,大多数人分布在两个城镇和两个大村庄。在大约115,000名居民中,约38%年龄在15岁以下,7.75%年龄在65岁以上。本研究采用药物追踪方法。所有正在服用抗帕金森病药物的人都被识别出来,并由神经科医生进行检查以确诊。

结果

该人群中帕金森病的总体粗患病率较低,为43.24/10万,而65岁以上年龄组的患病率为477.32/10万。在这个年龄以下,患病率非常低,为12.29/10万。帕金森病的患病率男性高于女性(比例为1.17);63%的男性患者吸烟。在农村地区居民中,患病率是其他地区的两倍,那里的大多数居民从事农业工作。

结论

以色列阿拉伯人群中帕金森病的患病率被认为较低,与其他阿拉伯国家报告的患病率相当。

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