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韩国老年人原发性震颤的患病率。

The prevalence of essential tremor in elderly Koreans.

作者信息

Oh Eung Seok, Kim Jong-Min, Kim Young Eun, Yun Ji Young, Kim Ji Seon, Kim Sang Eun, Lee Seok Bum, Lee Jung Jae, Park Joon Hyuk, Kim Tae Hui, Kim Ki Woong, Jeon Beom S

机构信息

Department of Neurology, Chungnam National University School of Medicine, Chungnam National University Hospital, Daejeon, Korea.

Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

出版信息

J Korean Med Sci. 2014 Dec;29(12):1694-8. doi: 10.3346/jkms.2014.29.12.1694. Epub 2014 Nov 21.

Abstract

Essential tremor (ET) is one of the most common movement disorders. The prevalence of ET varies substantially among studies. In Korea, there is no well-designed epidemiological study of the prevalence of ET. Thus, we investigated the prevalence of ET in a community in Korea. Standardized interviews and in-person neurological examinations were performed in a random sample of the elderly aged 65 yr or older. Next, movement specialists attempted to diagnose ET clinically. People who showed equivocal parkinsonian features underwent dopamine transporter imaging using [(123)I]-FP-CIT SPECT, to differentiate ET from parkinsonism. A total of 714 subjects participated in this population-based study. Twenty six of these subjects were diagnosed as having ET. The crude prevalence of ET was 3.64 per 100 persons. Age, gender, or education period were not different between the ET patients and the non-ET subjects. The prevalence of ET was slightly lower than those reported in previous studies. Further studies including more subjects are warranted.

摘要

特发性震颤(ET)是最常见的运动障碍之一。不同研究中ET的患病率差异很大。在韩国,尚无关于ET患病率的精心设计的流行病学研究。因此,我们调查了韩国一个社区中ET的患病率。对65岁及以上老年人的随机样本进行了标准化访谈和现场神经学检查。接下来,运动专家尝试进行ET的临床诊断。表现出模棱两可的帕金森病特征的人接受了使用[(123)I]-FP-CIT SPECT的多巴胺转运体成像,以区分ET和帕金森病。共有714名受试者参与了这项基于人群的研究。其中26名受试者被诊断患有ET。ET的粗患病率为每100人中有3.64人。ET患者与非ET受试者之间的年龄、性别或受教育年限没有差异。ET的患病率略低于先前研究报告的患病率。有必要开展包括更多受试者的进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b887/4248593/3acb0f1029b3/jkms-29-1694-g001.jpg

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