Uzun Hakan, Yazici Burhan, Erdogmus Besir, Kocabay Kenan, Buyukkaya Ramazan, Buyukkaya Ayla, Yazgan Omer
Duzce University School of Medicine, Department of Pediatrics, Konuralp, Duzce 81620, Turkey.
Eur J Radiol. 2009 Sep;71(3):552-6. doi: 10.1016/j.ejrad.2008.06.004. Epub 2008 Sep 27.
The aim of this study was to investigate the effect of fatty infiltration of the liver (FIL) on the Doppler waveform pattern in the hepatic veins of obese children.
In this prospective study, 59 patients with diffuse FIL and 45 normal healthy children who served as control group underwent hepatic vein B-mod and duplex Doppler sonography. The Doppler sonography spectrum of the right hepatic vein was classified into three groups: triphasic waveform, biphasic waveform, and monophasic or flat waveform.
There was a statistically significant difference in the phasicity of hepatic venous flow between patients and control subjects (p<0.001). The Doppler flow pattern in the right hepatic vein was triphasic in 28 (47.5%), biphasic in 28 (47.5%), and monophasic in 3 (5%) children with fatty liver, while it was triphasic in 43 (95.6%) and biphasic in 2 (4.4%) control subjects. There was an inverse correlation between the sonographic grade of fatty infiltration of the liver and the phasicity of hepatic venous flow (r=-0.479, p<0.001).
Abnormal right hepatic vein Doppler waveform, biphasic as well as monophasic, can be seen in healthy obese children with diffuse FIL.
本研究旨在探讨肝脏脂肪浸润（FIL）对肥胖儿童肝静脉多普勒波形模式的影响。
在这项前瞻性研究中，59例弥漫性FIL患者和45名正常健康儿童作为对照组接受了肝静脉B超和双功多普勒超声检查。右肝静脉的多普勒超声频谱分为三组：三相波形、双相波形和单相或平坦波形。
患者与对照组之间肝静脉血流的阶段性存在统计学显著差异（p<0.001）。脂肪肝患儿右肝静脉的多普勒血流模式为三相的有28例（47.5%），双相的有28例（47.5%），单相的有3例（5%），而对照组中三相的有43例（95.6%），双相的有2例（4.4%）。肝脏脂肪浸润的超声分级与肝静脉血流的阶段性呈负相关（r=-0.479，p<0.001）。
在患有弥漫性FIL的健康肥胖儿童中可观察到右肝静脉多普勒波形异常，包括双相和单相波形。
