Kriukova I N, Razvorotnev V A, Lavrovskiĭ V A
Vopr Virusol. 1976 Sep-Oct(5):580-4.
Expression of the main structural proteins of mammary gland cancer virus, gp52 and p27, was studied with the immune sera to these proteins in homogenates of tumors from mice of low and high cancer lines. Protein gp52 was found only in tumors of mice-carriers of MTV-S. In a fraction of purified type A particles from the cytoplasm of mammary gland cancer no gp52 was found, but with the antiserum to p27 this fraction reacted by a line identical to that with the antigen from C2HF mouse tumor.
利用针对这些蛋白质的免疫血清,对低癌系和高癌系小鼠肿瘤匀浆中乳腺癌病毒主要结构蛋白gp52和p27的表达进行了研究。仅在MTV-S携带小鼠的肿瘤中发现了蛋白质gp52。在从乳腺癌细胞质中纯化的A型颗粒组分中未发现gp52,但用抗p27血清检测时,该组分与来自C2HF小鼠肿瘤的抗原产生了相同的反应线。