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[静脉注射免疫球蛋白在治疗新生儿化脓性感染中的疗效]

[Immunoglobulin efficacy for intravenous administration in the therapy of newborn infants with a suppurative infection].

作者信息

Feklisova L V, Pokatilova A I, Iurina T M, Kiseleva I A, Shabalin V N

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1991 Apr(4):53-6.

PMID:1882610
Abstract

The data on the results of clinico-immunological examination of 46 infants having purulent inflammatory infections in the first month of their life and treated with (a) immunoglobulin for intravenous injection, (b) with hyperimmune antistaphylococcal plasma and immunoglobulin for intravenous injection and (c) without the use of specific hyperimmune preparations are presented. The clinico-laboratory data thus obtained (the levels of serum immunoglobulins and the content of T-rosette-forming lymphocytes) are indicative of the expediency of including the intravenous injection of donor immunoglobulin into the complex therapy of newborn infants with severe and moderate forms of purulent inflammatory infections at an early period of the disease irrespective of its etiology.

摘要

本文呈现了46例出生后首月患有化脓性炎症感染婴儿的临床免疫检查结果数据,这些婴儿分别接受了以下治疗:(a)静脉注射免疫球蛋白;(b)静脉注射超免疫抗葡萄球菌血浆和免疫球蛋白;(c)未使用特异性超免疫制剂。由此获得的临床实验室数据(血清免疫球蛋白水平和T花环形成淋巴细胞含量)表明,对于患有严重和中度化脓性炎症感染的新生儿,无论病因如何,在疾病早期将静脉注射供体免疫球蛋白纳入综合治疗是合理的。

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