Kelly Steven, Dwerryhouse Simon, Safranek Peter, Hardwick Richard
Cambridge Oesophagogastric surgery centre, Addenbrookes hospital, Cambridge, UK.
J Med Case Rep. 2008 Sep 30;2:314. doi: 10.1186/1752-1947-2-314.
Juvenile polyposis syndrome(JPS) is a rare autosomal dominant inherited condition. Hamartomatous polyps can affect the entire gastrointestinal tract but usually predominate in the colon. In this case report we present an unusual case of JPS that presented with massive gastric polyposis requiring a total gastrectomy.
A 51-year-old man presented with symptoms of gastric outlet obstruction and upper gastrointestinal bleeding. Gastroscopy showed massive gastric polyposis with a large antral polyp that had prolapsed through the pylorus causing gastric outlet obstruction. Initially endoscopic polypectomy was performed, but due to progressive symptoms a total gastrectomy was then performed. Histology confirmed massive gastric juvenile polyposis.
Massive gastric polyposis is an uncommon manifestation of juvenile polyposis syndrome. This case illustrates important principles in managing this condition.
青少年息肉病综合征（JPS）是一种罕见的常染色体显性遗传疾病。错构瘤性息肉可累及整个胃肠道，但通常以结肠最为常见。在本病例报告中，我们呈现了一例不寻常的青少年息肉病综合征病例，该病例表现为大量胃息肉，需要进行全胃切除术。
一名51岁男性出现胃出口梗阻和上消化道出血症状。胃镜检查显示大量胃息肉，一个大的胃窦息肉已通过幽门脱垂，导致胃出口梗阻。最初进行了内镜下息肉切除术，但由于症状进展，随后进行了全胃切除术。组织学检查证实为大量胃青少年息肉病。
大量胃息肉是青少年息肉病综合征的一种罕见表现。本病例说明了处理这种疾病的重要原则。
