Hauck Erik F, Vu Lisa, Campbell Gerald A, Nauta Haring J
Department of Neurosurgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-8855, USA.
J Clin Neurosci. 2008 Nov;15(11):1291-3. doi: 10.1016/j.jocn.2007.09.013. Epub 2008 Oct 1.
Gangliogliomas are mixed tumors consisting of both glial elements and differentiated neurons. Although any part of the central nervous system can be affected, little is known about intraventricular gangliogliomas. A patient with a ganglioglioma is presented in the previously unreported location of the anterior third ventricle at the foramen of Monro, mimicking a colloid cyst. We review all other reported cases of intraventricular ganglioglioma (n=6) to characterize this entity. Intraventricular gangliogliomas typically affect younger patients with female predominance (male:female, 2:5; median age 25 years). Symptoms occur secondary to obstruction of physiological cerebrospinal fluid circulation. Complete surgical resection with re-establishment of cerebrospinal fluid drainage is the goal of treatment.
神经节胶质瘤是由神经胶质成分和分化的神经元组成的混合性肿瘤。尽管中枢神经系统的任何部位都可能受累,但关于脑室内神经节胶质瘤的了解却很少。本文报告了一例神经节胶质瘤患者,肿瘤位于以前未报告过的孟氏孔处的第三脑室前部,类似胶样囊肿。我们回顾了所有其他已报告的脑室内神经节胶质瘤病例(n = 6),以对该实体进行特征描述。脑室内神经节胶质瘤通常影响较年轻的患者,女性居多(男:女,2:5;中位年龄25岁)。症状是由于生理性脑脊液循环受阻继发产生的。治疗的目标是通过重建脑脊液引流进行完整的手术切除。