Issa Jean-Pierre
University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.
Clin Cancer Res. 2008 Oct 1;14(19):5939-40. doi: 10.1158/1078-0432.CCR-08-1596.
Combined genetic and epigenetic analysis of sporadic colon cancer suggest that it can no longer be viewed as a single disease. There are at least three different subsets with distinct clinico-pathologic features, with important implications for preventions, screening, and therapy.
散发性结肠癌的基因和表观遗传联合分析表明，它不能再被视为单一疾病。至少存在三个具有不同临床病理特征的不同亚组，这对预防、筛查和治疗具有重要意义。
