Quigley M A, Kelly Y J, Sacker A
National Perinatal Epidemiology Unit, University of Oxford, Old Road Campus, Headington, Oxford OX3 7LF, UK.
Arch Dis Child. 2009 Feb;94(2):148-50. doi: 10.1136/adc.2008.146126. Epub 2008 Oct 1.
Most infants in the UK start solids before the recommended age of 6 months. We assessed the independent effects of solids and breast feeding on the risk of hospitalisation for infection in term, singleton infants in the Millennium Cohort Study (n = 15,980). For both diarrhoea and lower respiratory tract infection (LRTI), the monthly risk of hospitalisation was significantly lower in those receiving breast milk compared with those receiving formula. The monthly risk of hospitalisation was not significantly higher in those who had received solids compared with those not on solids (for diarrhoea, adjusted odds ratio 1.39, 95% CI 0.75 to 2.59; for LRTI, adjusted odds ratio 1.14, 95% CI 0.76 to 1.70), and the risk did not vary significantly according to the age of starting solids.
英国大多数婴儿在6个月的推荐年龄之前就开始添加辅食。在千禧队列研究(n = 15,980)中,我们评估了辅食和母乳喂养对足月儿、单胎婴儿感染住院风险的独立影响。对于腹泻和下呼吸道感染(LRTI),与接受配方奶的婴儿相比,接受母乳的婴儿每月住院风险显著更低。与未添加辅食的婴儿相比,已添加辅食的婴儿每月住院风险没有显著更高(腹泻方面,调整后的优势比为1.39,95%置信区间为0.75至2.59;LRTI方面,调整后的优势比为1.14,95%置信区间为0.76至1.70),且风险并未根据开始添加辅食的年龄而有显著差异。