Cornelius J R, Day N L, Fabrega H, Mezzich J, Cornelius M D, Ulrich R F
Western Psychiatric Institute and Clinic, University of Pittsburgh, Pa. 15213.
Arch Gen Psychiatry. 1991 Aug;48(8):749-53. doi: 10.1001/archpsyc.1991.01810320073011.
We present a first comprehensive description of the clinical features of patients with organic delusional syndrome. This description is based on information from 39 patients with organic delusional syndrome among 14,889 patients who presented for initial evaluation over a 5-year period at our institution. This description includes an enumeration of the common clinical symptoms of this syndrome and the respective prevalence and mean severity of each symptom. The severity of the symptoms of organic delusional syndrome are compared with those of schizophrenia to determine which symptoms distinguish between these two diagnostic categories. Patients with organic delusional syndrome demonstrated significantly more symptoms of "acquired intellectual impairment," "impaired sensorium," and "hallucinations of smell, taste, or touch," while schizophrenic patients demonstrated more "flat affect," "emotional coldness," and "thought disorganization." In addition, associated factors are presented concerning demographics, modes of treatment, level of functioning, and current physical problems associated with organic delusional syndrome.
我们首次全面描述了器质性妄想综合征患者的临床特征。这一描述基于我们机构在5年期间接受初次评估的14889名患者中39例器质性妄想综合征患者的信息。该描述包括此综合征常见临床症状的列举，以及每种症状的相应患病率和平均严重程度。将器质性妄想综合征的症状严重程度与精神分裂症的症状严重程度进行比较，以确定哪些症状可区分这两种诊断类别。器质性妄想综合征患者表现出明显更多的“获得性智力损害”“感觉障碍”和“嗅觉、味觉或触觉幻觉”症状，而精神分裂症患者表现出更多的“情感平淡”“情感冷漠”和“思维紊乱”症状。此外，还介绍了与器质性妄想综合征相关的人口统计学、治疗方式、功能水平和当前身体问题等相关因素。
