Dorosevich A E, Golubev O A
Arkh Patol. 1991;53(5):74-7.
Morphology of mammary fibroadenoma (FA) is well studied while this is not the case for its morphogenesis and prognosis. The role of a stromal component in the development of FA is outlined. Immune response in FA is mainly directed to the fibroblasts. Further studies of mammary FA will allow one to reveal the biological properties of this tumour and to evaluate adequately its prognosis as in 0.5-2% of cases it undergoes malignant transformation.
乳腺纤维腺瘤(FA)的形态学已得到充分研究,但其形态发生和预后情况并非如此。概述了基质成分在FA发生发展中的作用。FA中的免疫反应主要针对成纤维细胞。对乳腺FA的进一步研究将有助于揭示该肿瘤的生物学特性,并充分评估其预后,因为在0.5%-2%的病例中它会发生恶性转化。