Fiks A F
Vopr Onkol. 1975;21(10):13-5.
To study sarcomagenesis of the mammary gland and estimate the degree of maturity of its various stages, the author examined 45 postoperative specimens of fibroadenomatosis, fibroadenoma, leaf-shape tumor, sarcoma from the preexisting leaf-shape tumor and stromal sarcoma. Studies on the nucleus-plasma relationship, the mitotic coefficient, frequency and pathology of mitosis and quantitative-qualitative changes in sex chromatin allowed a more reliable estimation of the degree of maturity of cell elements of the fibroblastic origin in the process of malignant transformation.
为研究乳腺肉瘤的发生并评估其不同阶段的成熟程度，作者检查了45例术后标本，包括纤维腺瘤病、纤维腺瘤、叶状肿瘤、由先前叶状肿瘤发展而来的肉瘤以及间质肉瘤。对核质关系、有丝分裂系数、有丝分裂的频率和病理学以及性染色质的定量 - 定性变化进行研究，有助于更可靠地评估成纤维细胞起源的细胞成分在恶性转化过程中的成熟程度。
