Vanderbilt University Medical Center Department of Orthopaedic Surgery, Nashville, Tennessee 37232-8774, USA.
J Arthroplasty. 2009 Oct;24(7):1079-85. doi: 10.1016/j.arth.2008.08.010. Epub 2008 Oct 1.
Currently, porous tantalum (trabecular metal) implants are widely accepted and frequently used for primary and revision hip and knee replacement surgery. This study examines the results of porous tantalum endoprostheses used to reconstruct large skeletal defects following resection of bone tumors. Seven custom tantalum implants were used to reconstruct 7 patients following resection for skeletal sarcomas in the femur and proximal tibia. Patient ages ranged from 13 to 71, with a mean of 34 years. Minimum patient follow-up was 6 years. The average Musculoskeletal Tumor Society functional evaluation score was 95 % of normal. There were no infections, hardware failures, or adverse events. One implant was revised 98 months post insertion because of fibrosis, loss of motion and loosening. In this small clinical series, the use of porous tantalum for limb salvage reconstruction is shown to be safe, to successfully provide osteointegration and soft tissue ingrowth, and to facilitate return of limb girdle muscle function.
目前,多孔钽(多孔金属)植入物被广泛接受,并经常用于初次和翻修髋关节和膝关节置换手术。本研究检查了多孔钽内假体用于重建骨肿瘤切除后大的骨骼缺损的结果。在股骨和胫骨近端的骨骼肉瘤切除后,使用 7 个定制的钽植入物对 7 名患者进行了重建。患者年龄从 13 岁到 71 岁,平均 34 岁。患者的随访时间最短为 6 年。肌肉骨骼肿瘤学会(Musculoskeletal Tumor Society)的平均功能评估评分为正常的 95%。没有感染、硬件失败或不良事件。一个植入物在插入后 98 个月因纤维化、运动丧失和松动而进行了翻修。在这个小的临床系列中,多孔钽用于肢体挽救性重建是安全的,成功地提供了骨整合和软组织长入,并促进了肢体带肌功能的恢复。