Hall Tanya D, Mahony Orla, Rozanski Elizabeth A, Freeman Lisa M
Department of Clinical Sciences, Tufts Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, United States.
J Feline Med Surg. 2009 Feb;11(2):125-30. doi: 10.1016/j.jfms.2008.06.009. Epub 2008 Oct 1.
The purpose of this study was to evaluate the effects of dietary modification in addition to twice daily insulin glargine. Cats were treated with insulin glargine twice daily and randomized to receive either a low carbohydrate, high protein (LCHP) diet (n=6) or a control diet (n=6) for 10 weeks. Re-evaluations of clinical signs, blood glucose curves, and serum fructosamine concentrations were performed at weeks 1, 2, 4, 6, and 10. Two of 12 cats achieved complete remission by the end of the study but remission rate was not different between diet groups. Using twice daily insulin glargine and frequent monitoring, all cats in both diet groups achieved successful glycemic control. Frequent monitoring is key to achieving glycemic control in diabetic cats; potential benefits of dietary modification require further evaluation.
本研究的目的是评估除每日两次甘精胰岛素之外的饮食调整的效果。猫每天接受两次甘精胰岛素治疗，并随机分为两组，一组接受低碳水化合物、高蛋白（LCHP）饮食（n = 6），另一组接受对照饮食（n = 6），为期10周。在第1、2、4、6和10周对临床症状、血糖曲线和血清果糖胺浓度进行重新评估。到研究结束时，12只猫中有2只实现了完全缓解，但饮食组之间的缓解率没有差异。通过每日两次使用甘精胰岛素并频繁监测，两个饮食组的所有猫都实现了成功的血糖控制。频繁监测是糖尿病猫实现血糖控制的关键；饮食调整的潜在益处需要进一步评估。
