Romano Gaetano
Sbarro Institute for Cancer Research and Molecular Medicine, College of Science and Technology, Temple University, Philadelphia 19122, USA.
Drug News Perspect. 2008 Jul-Aug;21(6):345-51. doi: 10.1358/dnp.2008.21.6.1260760.
The 11th Annual Meeting of the American Society of Gene Therapy focused on clinical trials for the treatment of various pathological conditions, preclinical studies, use of gene transfer technology for genetic immunization purposes and problems related to the improvement of vector design. In this respect, a major emphasis was placed on safety issues, such as insertional mutagenesis and host immune responses to gene delivery systems.
美国基因治疗学会第11届年会聚焦于针对各种病理状况的临床试验、临床前研究、用于基因免疫目的的基因转移技术的应用以及与改进载体设计相关的问题。在这方面,重点主要放在安全问题上,如插入诱变和宿主对基因递送系统的免疫反应。