Eleni-dit-Trolli S, Kermorvant-Duchemin E, Huon C, Mokthari M, Husseini K, Brunet M-L, Dupont C, Lapillonne A
Department of Neonatology and Nutrition, Saint-Vincent de Paul Hospital, 74 Avenue Denfert Rochereau, Paris, France.
Arch Dis Child Fetal Neonatal Ed. 2009 Mar;94(2):F152-3. doi: 10.1136/adc.2007.136333. Epub 2008 Oct 6.
Considerable effort should be made to optimise parenteral nutrition of preterm infants in order to limit the development of postnatal growth restriction. A monocentric before-and-after study design was used to determine the effects of computerising parenteral nutrition ordering on the composition of parenteral nutrition (PN) solutions and early clinical outcomes of preterm infants born < or =28 weeks of gestation. Parenteral protein intake during the first week of life and parenteral lipid, glucose and energy intakes during the first and second week of life were significantly higher in infants assessed after the introduction of computerised parenteral nutrition ordering. This led to a significant reduction in the cumulative energy deficit over the first 28 days of life and to an improvement in both early growth and pulmonary outcome. Computerising the PN ordering process improves the nutrient content of the PN solutions and early postnatal outcome.
应付出相当大的努力来优化早产儿的肠外营养，以限制出生后生长受限的发展。采用单中心前后对照研究设计，以确定肠外营养医嘱计算机化对孕周小于或等于28周的早产儿肠外营养（PN）溶液成分及早期临床结局的影响。在引入肠外营养医嘱计算机化后评估的婴儿中，出生后第一周的肠外蛋白质摄入量以及出生后第一周和第二周的肠外脂肪、葡萄糖和能量摄入量显著更高。这导致出生后前28天累积能量 deficit 显著减少，并使早期生长和肺部结局均得到改善。将PN医嘱流程计算机化可改善PN溶液的营养成分及出生后早期结局。
