Department of Social Policy and Social Work, University of Oxford, Oxford, Oxfordshire, England.
AIDS Behav. 2010 Feb;14(1):1-10. doi: 10.1007/s10461-008-9471-4.
HIV is frequently transmitted in the context of partners in a committed relationship, thus couples-focused HIV prevention interventions are a potentially promising modality for reducing infection. We conducted a systematic review of studies testing whether couples-focused behavioral prevention interventions reduce HIV transmission and risk behavior. We included studies using randomized controlled trial designs, quasi-randomized controlled trials, and nonrandomized controlled studies. We searched five electronic databases and screened 7,628 records. Six studies enrolling 1,084 index couples met inclusion criteria and were included in this review. Results across studies consistently indicated that couples-focused programs reduced unprotected sexual intercourse and increased condom use compared with control groups. However, studies were heterogeneous in population, type of intervention, comparison groups, and outcomes measures, and so meta-analysis to calculate pooled effects was inappropriate. Although couples-focused approaches to HIV prevention appear initially promising, additional research is necessary to build a stronger theoretical and methodological basis for couples-focused HIV prevention, and future interventions must pay closer attention to same-sex couples, adolescents, and young people in relationships.
HIV 经常在有承诺关系的伴侣中传播，因此针对伴侣的 HIV 预防干预措施是减少感染的一种潜在有效方式。我们对测试针对伴侣的行为预防干预措施是否减少 HIV 传播和风险行为的研究进行了系统回顾。我们纳入了使用随机对照试验设计、准随机对照试验和非随机对照研究的研究。我们检索了五个电子数据库并筛选了 7628 条记录。有 6 项纳入 1084 对索引夫妇的研究符合纳入标准并被纳入本综述。研究结果一致表明，与对照组相比，针对伴侣的项目减少了无保护性行为并增加了 condom 的使用。然而，研究在人群、干预类型、对照组和结果测量方面存在异质性，因此不适合进行荟萃分析以计算汇总效果。尽管针对伴侣的 HIV 预防方法似乎最初很有希望，但需要进一步研究为针对伴侣的 HIV 预防建立更强的理论和方法基础，未来的干预措施必须更加关注同性伴侣、青少年和处于关系中的年轻人。
