Qui Yong, Qiu Xu-sheng, Sun Xu, Wang Bin, Yu Yang, Zhu Ze-zhang, Qian Bang-ping, Zhu Feng, Liu Zhen
Department of Orthopaedics, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China.
Zhonghua Wai Ke Za Zhi. 2008 Apr 15;46(8):588-91.
To investigate body weight and the body mass index (BMI) in girls with adolescent idiopathic scoliosis (AIS).
Six hundred and thirteen AIS female patients admitted from January 2005 to January 2007 and 449 healthy girls were recruited for this study with a range of age from 12 to 16 years old. The direct indexes included body height, body weight and date of birth. The indirect indexes included corrected body height, BMI and corrected BMI. The corrected body heights of AIS patients were adjusted by using the greatest Cobb angle to correct for spinal deformity according to Bjure's formula. Two-tailed Student's test was used for group comparison.
In the AIS patients, the maximum Cobb angle was (31 +/- 11) degrees (11 degrees to 77 degrees). The corrected body height were significantly higher in AIS patients than in the normal controls from 12 to 16 years old (P < 0.05). The body weight were significantly lower in AIS girls than in normal controls from 12 to 16 years of age (P < 0.01). From 12 to 16 years of age, the BMI were (17.6 +/- 1.9), (17.9 +/- 2.5), (17.9 +/- 2.1), (18.6 +/- 2.3) and (19.0 +/- 1.9) kg/m2 in AIS patients; while the BMI were (19.5 +/- 3.4), (19.8 +/- 3.0), (20.4 +/- 2.9), (20.4 +/- 2.8) and (20.2 +/- 2.2) kg/m2 in normal controls. The BMI were significantly lower in AIS girls than the normal controls from 12 to 16 years of age (P < 0.001).
After the onset of puberty, significantly longer corrected height, lower body weight and lower BMI were found in AIS patients. Results of this large-scale study revealed the presence of abnormal growth in AIS patients during peripubertal development.
研究青少年特发性脊柱侧凸（AIS）女孩的体重和体重指数（BMI）。
选取2005年1月至2007年1月收治的613例AIS女性患者和449例健康女孩作为研究对象，年龄范围为12至16岁。直接指标包括身高、体重和出生日期。间接指标包括矫正身高、BMI和矫正BMI。AIS患者的矫正身高根据比尤尔公式，用最大Cobb角校正脊柱畸形后得出。采用双侧t检验进行组间比较。
AIS患者的最大Cobb角为（31±11）度（11度至77度）。12至16岁AIS患者的矫正身高显著高于正常对照组（P<0.05）。12至16岁AIS女孩的体重显著低于正常对照组（P<0.01）。12至16岁，AIS患者的BMI分别为（17.6±1.9）、（17.9±2.5）、（17.9±2.1）、（18.6±2.3）和（19.0±1.9）kg/m²；而正常对照组的BMI分别为（19.5±3.4）、（19.8±3.0）、（20.4±2.9）、（20.4±2.8）和（{20.2±2.2}）kg/m²。12至16岁AIS女孩的BMI显著低于正常对照组（P<0.001）。
青春期开始后，AIS患者的矫正身高显著更长，体重和BMI更低。这项大规模研究的结果揭示了AIS患者在青春期发育期间存在异常生长。
