Greig Samuel R, Chaplin John M, McIvor Nicholas P, Izzard Mark E, Taylor Graham, Wee Desmond
Department of Otolaryngology, Head and Neck Surgery, Auckland City Hospital, Auckland, New Zealand.
ANZ J Surg. 2008 Sep;78(9):754-8. doi: 10.1111/j.1445-2197.2008.04643.x.
Acinic cell carcinoma is an uncommon malignancy of the salivary glands and as such it has been difficult to accurately delineate its natural history. The aim of this study is to assess the behaviour of acinic cell salivary cancer of the parotid gland presenting to a single head and neck surgical unit in Auckland. The study is a structured review of cases of acinic cell carcinoma of the parotid gland presenting from 2000 to 2006 to the Head and Neck Unit at Auckland Hospital, those identified from the pathology database and the Otobase head and neck database. Case records and pathology reports were reviewed. Fifteen patients were identified, 9 men and 6 women. The mean age was 67.2 years, with range 50-85 years. The mean follow up was 4.4 years and range 1.1-7 years. There was one case of local recurrence during study period and no deaths. Five of 15 patients received postoperative radiotherapy. Postoperative complications consisted of one wound haematoma and two cases of marginal mandibular weakness (one transient and one permanent). Current management strategies are obtaining appropriate rates of recurrence and postoperative complications within the Auckland population.
腺泡细胞癌是一种罕见的唾液腺恶性肿瘤,因此很难准确描述其自然病程。本研究的目的是评估在奥克兰一家头颈外科单位就诊的腮腺腺泡细胞唾液腺癌的行为。该研究是对2000年至2006年在奥克兰医院头颈科就诊的腮腺腺泡细胞癌病例、从病理数据库和Otobase头颈数据库中识别出的病例进行的结构化回顾。对病例记录和病理报告进行了审查。共识别出15例患者,9名男性和6名女性。平均年龄为67.2岁,范围为50 - 85岁。平均随访时间为4.4年,范围为1.1 - 7年。研究期间有1例局部复发,无死亡病例。15例患者中有5例接受了术后放疗。术后并发症包括1例伤口血肿和2例下颌缘支神经麻痹(1例短暂性,1例永久性)。目前的管理策略在奥克兰人群中获得了适当的复发率和术后并发症发生率。